8.8
HIGH CVSS 3.1
CVE-2025-54307
Thermo Fisher Torrent Suite Remote Code Execution Vulnerability
Description

An issue was discovered in the Thermo Fisher Torrent Suite Django application 5.18.1. The /configure/plugins/plugin/upload/zip/ and /configure/newupdates/offline/bundle/upload/ endpoints allow low-privilege users to upload ZIP files to the server. The plupload_file_upload function handles these file uploads and constructs the destination file path by using either the name parameter or the uploaded filename, neither of which is properly sanitized. The file extension is extracted by splitting the filename, and a format string is used to construct the final file path, leaving the destination path vulnerable to path traversal. An authenticated attacker with network connectivity can write arbitrary files to the server, enabling remote code execution after overwriting an executable file. An example is the pdflatex executable, which is executed through subprocess.Popen in the write_report_pdf function after requests to a /report/latex/(\d+).pdf endpoint.

INFO

Published Date :

Dec. 4, 2025, 3:15 p.m.

Last Modified :

Dec. 16, 2025, 6:46 p.m.

Remotely Exploit :

Yes !
Affected Products

The following products are affected by CVE-2025-54307 vulnerability. Even if cvefeed.io is aware of the exact versions of the products that are affected, the information is not represented in the table below.

ID Vendor Product Action
1 Thermofisher torrent_suite_software
CVSS Scores
The Common Vulnerability Scoring System is a standardized framework for assessing the severity of vulnerabilities in software and systems. We collect and displays CVSS scores from various sources for each CVE.
Score Version Severity Vector Exploitability Score Impact Score Source
CVSS 3.1 HIGH 134c704f-9b21-4f2e-91b3-4a467353bcc0
Solution
Remediate path traversal by sanitizing user-supplied input for file uploads.
  • Sanitize all user-supplied input used in file paths.
  • Validate file extensions before constructing destination paths.
  • Implement strict access controls for file upload endpoints.
  • Update the application to a patched version.
CWE - Common Weakness Enumeration

While CVE identifies specific instances of vulnerabilities, CWE categorizes the common flaws or weaknesses that can lead to vulnerabilities. CVE-2025-54307 is associated with the following CWEs:

We scan GitHub repositories to detect new proof-of-concept exploits. Following list is a collection of public exploits and proof-of-concepts, which have been published on GitHub (sorted by the most recently updated).

Results are limited to the first 15 repositories due to potential performance issues.

The following list is the news that have been mention CVE-2025-54307 vulnerability anywhere in the article.

The following table lists the changes that have been made to the CVE-2025-54307 vulnerability over time.

Vulnerability history details can be useful for understanding the evolution of a vulnerability, and for identifying the most recent changes that may impact the vulnerability's severity, exploitability, or other characteristics.

  • Initial Analysis by [email protected]

    Dec. 16, 2025

    Action Type Old Value New Value
    Added CPE Configuration OR *cpe:2.3:a:thermofisher:torrent_suite_software:5.18.1:*:*:*:*:*:*:*
    Added Reference Type MITRE: https://assets.thermofisher.com/TFS-Assets/LSG/manuals/MAN0026163-Torrent-Suite-5.18-UG.pdf Types: Product, Release Notes
    Added Reference Type MITRE: https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/Ion_OneTouch_2_and_Torrent_Suite_Software.pdf Types: Vendor Advisory
    Added Reference Type MITRE: https://www.thermofisher.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-data-analysis-workflow/ion-torrent-suite-software.html Types: Product
  • CVE Modified by 134c704f-9b21-4f2e-91b3-4a467353bcc0

    Dec. 05, 2025

    Action Type Old Value New Value
    Added CVSS V3.1 AV:N/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H
    Added CWE CWE-22
  • New CVE Received by [email protected]

    Dec. 04, 2025

    Action Type Old Value New Value
    Added Description An issue was discovered in the Thermo Fisher Torrent Suite Django application 5.18.1. The /configure/plugins/plugin/upload/zip/ and /configure/newupdates/offline/bundle/upload/ endpoints allow low-privilege users to upload ZIP files to the server. The plupload_file_upload function handles these file uploads and constructs the destination file path by using either the name parameter or the uploaded filename, neither of which is properly sanitized. The file extension is extracted by splitting the filename, and a format string is used to construct the final file path, leaving the destination path vulnerable to path traversal. An authenticated attacker with network connectivity can write arbitrary files to the server, enabling remote code execution after overwriting an executable file. An example is the pdflatex executable, which is executed through subprocess.Popen in the write_report_pdf function after requests to a /report/latex/(\d+).pdf endpoint.
    Added Reference https://assets.thermofisher.com/TFS-Assets/LSG/manuals/MAN0026163-Torrent-Suite-5.18-UG.pdf
    Added Reference https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/Ion_OneTouch_2_and_Torrent_Suite_Software.pdf
    Added Reference https://www.thermofisher.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-data-analysis-workflow/ion-torrent-suite-software.html
EPSS is a daily estimate of the probability of exploitation activity being observed over the next 30 days. Following chart shows the EPSS score history of the vulnerability.
Vulnerability Scoring Details
Base CVSS Score: 8.8
Attack Vector
Attack Complexity
Privileges Required
User Interaction
Scope
Confidentiality Impact
Integrity Impact
Availability Impact